2023 Highlights

Montefiore Einstein Neurology

World-renowned Neurologists.
Elite Biomedical Scientists.
Life-changing Results.

The Saul R. Korey Department of Neurology created a visionary model of neurological care that enabled us to envision neurological diseases as lifespan disorders, forever changing the lens through which neurological diseases are understood. 

Childhood and early onset disorders necessitate different treatment modalities as the brain changes during adult life and aging. As medical breakthroughs have increased the median survival, our institution offers a destination site reflecting the aspiration that these patients can lead increasingly productive and fulfilling lives as they age. Research carried out in departmental laboratories has led to the paradigm-shifting discovery that aging likely starts at conception, and that the forerunners of late-onset dementias had their origin at the early stages of life, and account for the fact that these disorders in fact are systemic disorders that need to be treated in an interdisciplinary way. These revolutionary discoveries have profound implications for the early treatment of these currently untreatable conditions using a range of stem cell, epigenetic reprogramming and dynamic tissue remodeling strategies, thereby offering hope for the development of true disease-modifying treatments and even disease cures.

DATA & STATISTICS

2023 by the numbers

33,570

outpatient

35,873

inpatient

6,337

admissions

8,505

procedures

Creating Transformative Solutions to the
Intractable Challenges of Neurologic Disease

A premiere example of our global leadership, interdisciplinary collaborations, and commitment to the interdependence of neurologic disease, multigenerational inheritance, community integration and environmental contingencies is our recognition in innovative approaches to stroke research and clinical care.

Montefiore Einstein is spearheading and participating in numerous clinical trials to advance promising interventions for stroke prevention, treatment, recovery and rehabilitation for patients with or at risk of a stroke across all stages of life. We are a founding partner and key member of the New York City Collaborative Regional Coordinating Center (NYCC-RCC), the largest National Institutes of Health (NIH)-funded multi-institutional consortium dedicated to stroke prevention, treatment, education and rehabilitation efforts to reduce the burden of stroke on children and adults throughout the country. Distinguished as an inaugural NIH StrokeNet Regional Coordinating Center since the inception of this highly competitive NIH initiative (StrokeNet) in 2013, we are among an elite group of only 27 centers in the nation to be awarded a five-year grant funded by the National Institute of Neurological Disorders and Stroke (NINDS).

As one of the top NIH StrokeNet centers enrolling minority groups to ensure that a diverse population of patients is represented in our clinical trials, we are committed to serving children and adults who are underrepresented in stroke research, and to advancing culturally sensitive interventions and protocols for populations most at risk for stroke. We also continue to develop interdisciplinary endovascular platforms, new devices and intersectional strategies for conducting ultra-rapid clinical trials.

A collaborative effort between the NIH and Montefiore Einstein, the Icahn School of Medicine at Mount Sinai, New York University School of Medicine and other affiliated institutions and partner sites, our Regional Coordinating Center encompasses all boroughs of New York City, Westchester, Long Island and Upstate New York, as well as Nashville, TN, and we continue to expand our network, leadership, and influence.

RESEARCH REVIEW

Improving care and outcomes through research

CLINICAL TRIALS

Transforming the landscape of clinical care

At the Saul R. Korey Department of Neurology, we are committed to finding new and innovative options to prevent, diagnose, treat and cure neurologic diseases. 

We are spearheading numerous clinical trials to advance treatments and receive notable NIH-funded grants, including our elite NINDS/NIH StrokeNet neurovascular clinical trials consortium grant.

We use these grants for the study of a wide range of neurological diseases including dementia, Alzheimer’s disease, epilepsy, Multiple Sclerosis, and Huntington’s disease, as well as research that examines novel ways to restore brain function and studies that target the effects of COVID-19 on the brain in those with mild or asymptomatic infection.

Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)

Open-Label Extension Study of Trofinetide for Rett Syndrome

Pharmacological Treatment of Rett Syndrome With Glatiramer Acetate (Copaxone)

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LILAC™)

Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™)

Pharmacological Treatment of Rett Syndrome With Statins (Statins)

A Long-term Safety Study of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome

Efficacy and Safety of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome (ARCH)

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis

A Phase 2/3 Randomized, Double-Blind, Placebo- Controlled Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study of BOTOX (Botulinum Toxin Type A) for the Prevention of Migraine in Subjects with Episodic Migraine

A Phase 4 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Rimegepant in Episodic Migraine Prevention with Multiple Dosing Regimens

Interventional, Randomized, Double-blind, Parallel-group, Placebo-controlled study of Add-on Eptinezumab Treatment to Brief Education Intervention, for the Preventive Treatment of Migraine in Patients with a Dual Diagnosis

A Phase 4, Randomized, Double-blind Placebo-Controlled, Efficacy and Tolerability Trial of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use

A Phase 4, Randomized, Doubleblind, Placebo-controlled Study to Evaluate the Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults with a History of Inadequate Response to Oral Preventive Medications

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Rimegepant in Migraine Prevention in Children and Adolescents = 6 to <18 Years of Age

Phase 4, Open-label Study to Evaluate Treatment Satisfaction With Erenumab in Patients With Migraine

Team News

Updates and additions to our world-renowned faculty

Donya Eizadkhah, MD

Child Neurology

Adilia Hormigo, MD, PhD

Neuro-oncology

Kristina M. Maselli, MD

Headache and Sleep Medicine

Neil R. Patel, MD

Hospitalist and Epilepsy

Johanna M. Seiden, MD

Vascular Neurology

Michael S. Tau, MD

Neuropsychiatry

Saroj D. Kunnakkat, DO, MS

Epilepsy

Joshua K. Rim, MD

Neuromuscular Medicine

Patient referrals

Montefiore Einstein Saul R. Korey Department of Neurology, we know providing patients with the best possible care includes teamwork and trust. We work closely with our valued referring physicians to ensure open communication and reliable expertise. 

Contact Us

Mark F. Mehler MD, Chair, Neurology
mark.mehler@einsteinmed.edu

Montefiore Einstein Neurology